ZIA CP010133-04094 (ZIA) | |||
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Title | Chornobyl Leukemia Study | ||
Institution | NCI, Bethesda, MD | ||
Principal Investigator | Mabuchi, Kiyohiko | NCI Program Director | N/A |
Cancer Activity | N/A | Division | DCEG |
Funded Amount | $335,420 | Project Dates | 01/01/1999 - N/A |
Fiscal Year | 2012 | Project Type | Intramural |
Research Topics w/ Percent Relevance | Cancer Types w/ Percent Relevance | ||
Biochemical Epidemiology (45.0%) Cancer (100.0%) Radiation - Ionizing - Total (100.0%) Radiation - Ionizing Low Level (100.0%) |
Leukemia (100.0%) | ||
Research Type | |||
Exogenous Factors in the Origin and Cause of Cancer Surveillance |
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Abstract | |||
Leukemia is one of the cancer sites most sensitive to the carcinogenic effect of ionizing radiation, and has the shortest latent period among radiation-induced cancers. A nested case control study of Leukemia has recently been completed in a cohort of approximately 110,000 men in Ukraine who participated in the clean-up operations following the Chornobyl accident. Leukemias and other hematological disorders have been identified from clinical records and the National Cancer Registry and confirmed by a panel of international experts. Bone marrow doses were estimated using a method called RADRUE (Radiation Dose Reconstruction with Uncertainty Estimates). Analysis and manuscript preparation are underway for publication. |